A new treatment for lung scarring due to Covid-19 infection
NY
RT1840 is a repurposed, safe compound, formulated as an inhaled product to directly administer to the lung to prevent/reverse scarring (fibrosis)
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<ul> <li>RT175, the key API in our treatment, was originally developed as an oral medication for the treatment of neural degenerative diseases, beginning in 2002</li> <li>Human clinical experience: <ul> <li>611 people exposed to doses ranging from 100mg to 6g <ul> <li>Safe and well-tolerated</li> </ul> </li> <li>4 Phase 1 safety and PK studies</li> <li>4 Phase 2 Studies in Parkinson Disease and post-prostatectomy ED</li> <li>Longest and highest exposure was 4g/day for 2 years <em>po</em></li> </ul> </li> <li>Over $138MM spent on development to date</li> <li>Full IND-enabling safety, toxicology and and PK/PD packages</li> <li>Based on unexpected and results in animal studies, the drug was repurposed to a low-dose aerosol to treat pulmonary fibrosis <ul> <li>New formulation</li> <li>IP well protected</li> </ul> </li> </ul> <p> </p>
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