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Allena Pharmaceuticals

Allena Pharmaceuticals

Oral enzymes for kidney disease

Newton, Massachusetts, US

Allena Pharmaceuticals develops non-systemic protein therapeutics for metabolic and orphan diseases.

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How We Help

Problem Statement

Patients with rare and severe metabolic and kidney disorders suffer from the excess accumulation of metabolites like oxalate and urate, which can cause kidney stones, kidney damage, chronic kidney disease (CKD), and end-stage renal disease.

Core Technology

Oral enzyme therapeutics

Key Differentiators

First-in-class, oral enzyme therapeutics to treat patients with rare and severe metabolic and kidney disorders

Clinical Focus

Nephrology; Metabolic Disorders

Company Info

Total Funding
40,000,000
Website
allenapharma.com

Categories

Drug Discovery/Development

Disease Areas

Technologies

Oral Enzyme TherapeuticsBiopharmaceuticaloral enzyme therapeuticsbiopharmaceutical

Clinical & IP

🔬

Clinical Validation

Lead candidate reloxaliase in Phase 3 (URIROX-2) with positive Phase 2 data and FDA accelerated approval pathway alignment. ALLN-346 has FDA Fast Track designation for gout-CKD indication. Demonstrated efficacy in reducing urinary oxalate and managing hyperuricemia.

MedStartr Index Score

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47

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Innovation

Clinical Benefit

Feasibility

Scalability

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