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Allena Pharmaceuticals

Allena Pharmaceuticals

Oral enzymes for kidney disease

Newton, Massachusetts, US

Allena Pharmaceuticals develops non-systemic protein therapeutics for metabolic and orphan diseases.

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How We Help

Problem Statement

Patients with rare and severe metabolic and kidney disorders suffer from the excess accumulation of metabolites like oxalate and urate, which can cause kidney stones, kidney damage, chronic kidney disease (CKD), and end-stage renal disease.

Core Technology

Oral enzyme therapeutics

Key Differentiators

First-in-class, oral enzyme therapeutics to treat patients with rare and severe metabolic and kidney disorders

Clinical Focus

Nephrology; Metabolic Disorders

Company Info

Total Funding
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Website
allenapharma.com

Categories

Drug Discovery/Development

Disease Areas

Technologies

Oral Enzyme TherapeuticsBiopharmaceutical

Clinical & IP

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Clinical Validation

Lead candidate reloxaliase in Phase 3 (URIROX-2) with positive Phase 2 data and FDA accelerated approval pathway alignment. ALLN-346 has FDA Fast Track designation for gout-CKD indication. Demonstrated efficacy in reducing urinary oxalate and managing hyperuricemia.

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What do you think of Allena Pharmaceuticals?

A HUGE part of what early stage companies, and even late stage ones, need and get on MedStartr is honest feedback from actual patients, clinicians, hospital leaders and industry insiders. It is very easy to get tunnel vision as a founder. Please tell the team that runs this company what you think.

Clinical Benefit Potential

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Feasibility

The likelihood that this will provide benefit for patients / care givers and that the founders can execute on their vision and plan.

Innovativeness

The distinguishing features, concept, or technology that differentiates the entry compared to others that already exist and are in widespread use.

Fundability

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Scalability

Some great ideas are destined to failure because they are too complex or too expensive. The reviewer should consider the likelihood that a project as explained, or perhaps with some tweaks, could possibly become a worldwide solution within a reasonable time frame.

Presentation Quality

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