Aspisafe Solutions

Our lead product is a feeding tube that would prevent pneumonias in patients who are on life support in the ICU. Current feeding tubes in the market ironically facilitate pneumonias

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Check out Aspisafe Solutions on @MedStartr Today Our lead product is a feeding tube that would prevent pneumonias in patients who are on life support in the ICU. Current feeding tubes in the market  ironically facilitate pneumonias. #MedMo #MedStartrVentures

https://www.medstartr.ai/s/Bt9b_34wRZc

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proton pump inhibitors, gastric feeding, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217765/">gastric reflux</a> and the <a href="https://www.ahrq.gov/professionals/quality-patient-safety/hais/tools/mvp/modules/technical/head-bed-elevation-litreview.html">supine position</a>. Head of bed elevation on its own has been shown to reduce the risk of VAP indicating that gastric reflux plays a major part in this infectious process. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396145/">Two</a> prospective <a href="http://www.atsjournals.org/doi/full/10.1164/rccm.201104-0630OC">studies</a> showed that VAP is associated with more pepsin in tracheal aspirates indicating that VAP is related to aspiration of gastric contents. There is little doubt in our mind that preventing aspiration will help reduce VAP in the ICU. Aspisafe, not only helps reduce the risk of VAP, but it also helps confirm placement without the need for an xray. The user will know once he/she pulls back on the catheter and meets resistane that the catheter is in the right place. In addition, the production of <a href="https://www.ncbi.nlm.nih.gov/pubmed/12626984">saliva</a> is minimal in ventilated patients due to the medication effects and the lack of oral feeding. This minimises the effect of saliva aspiration in those patients. Aspisafe also has a side lumen to suction any saliva that trickles down the esophagus.      " placeholder="" maxlength="2000"> There are a multitude ot studies that show a strong correlation between gastric aspiration and ventilator associated pneumonia (VAP). A few strong correlations that have been shown to inrease those risks include the use of feeding tubes, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153243/">proton pump inhibitors</a>, gastric feeding, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217765/">gastric reflux</a> and the <a href="https://www.ahrq.gov/professionals/quality-patient-safety/hais/tools/mvp/modules/technical/head-bed-elevation-litreview.html">supine position</a>. Head of bed elevation on its own has been shown to reduce the risk of VAP indicating that gastric reflux plays a major part in this infectious process. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396145/">Two</a> prospective <a href="http://www.atsjournals.org/doi/full/10.1164/rccm.201104-0630OC">studies</a> showed that VAP is associated with more pepsin in tracheal aspirates indicating that VAP is related to aspiration of gastric contents. There is little doubt in our mind that preventing aspiration will help reduce VAP in the ICU. Aspisafe, not only helps reduce the risk of VAP, but it also helps confirm placement without the need for an xray. The user will know once he/she pulls back on the catheter and meets resistane that the catheter is in the right place. In addition, the production of <a href="https://www.ncbi.nlm.nih.gov/pubmed/12626984">saliva</a> is minimal in ventilated patients due to the medication effects and the lack of oral feeding. This minimises the effect of saliva aspiration in those patients. Aspisafe also has a side lumen to suction any saliva that trickles down the esophagus.

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Clinical Validation

There are a <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2396145/">multittude</a> of <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941480/">studies</a> out there that show aspiration of gastric contents increase the risk of ventilator associated pneumonia. I am happy to site those studies for anyone who asks. There is also a <a href="https://www.ncbi.nlm.nih.gov/pubmed/12626984">study</a> that shows how saliva production decreases to a minimum in intubated patients. These studies form the basis of the need for such a device. A <a href="http://journals.lww.com/anesthesia-analgesia/Fulltext/1995/02000/Can_Pulmonary_Aspiration_of_Gastric_Contents_Be.30.aspx">study</a> on pigs was conducted 22 years ago proving that a catheter with a balloon in the stomach is able to prevent aspiration of gastric contents after inducing gastric reflux via several mechanisms. A similar study can be conducted to prove efficacy of our device. Contact with several animal labs and contract research organisations have been initiated and some quotes obtained for such a study to be conducted.

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