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Anticipate. Evaluate. Treat. Early Intervention Means Better Care and Fewer Hospitalizations

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Clinical Validation

<p>There is a large body of literature that lead us to develop our algorithm, some of which I site below.</p> <p>The pilot study in March will be the first direct proof of efficacy.</p> <ul> <li>Schiff, Gordon D., et al. &quot;Decompensated heart failure: symptoms, patterns of onset, and contributing factors.&quot; <em>The American journal of medicine</em> 114.8 (2003): 625-630.</li> <li>Jehn, Melissa, et al. &quot;Association of physical activity and prognostic parameters in elderly patients with heart failure.&quot; <em>Journal of aging and physical activity</em> 19.1 (2011): 1-15.</li> <li>Chaudhry S, et al &quot;Risk factors for hospital admission among older persons with newly diagnosed heart failure findings from the cardiovascular health study&quot; J Am Coll Cardiol 2013; 61: 635-642.</li> <li>Passantino, Andrea, et al. &quot;Short-term change in distance walked in 6 min is an indicator of outcome in patients with chronic heart failure in clinical practice.&quot; <em>Journal of the American College of Cardiology</em> 48.1 (2006): 99-105.</li> <li>Hanly PJ, Zuberi-Khokhar N. Periodic limb movements during sleep in patients with congestive heart failure. Chest. 1996;109(6):1497&ndash;502</li> <li>Hanly, Patrick, and Naheed Zuberi-Khokhar. &quot;Daytime sleepiness in patients with congestive heart failure and Cheyne-Stokes respiration.&quot; <em>CHEST Journal</em> 107.4 (1995): 952-958.</li> <li>Redeker NS. Sleep disturbance in people with heart failure: implications for self- care. J Cardiovasc Nurs. 2008;23(3):231-238.</li> <li>Redeker NS, Jeon S, Muench U, Campbell D, Walsleben J, Rapoport D. Insomnia symptoms and daytime function in stable heart failure. Sleep. 2010;33.</li> <li>Erickson VS, Westlake CA, Dracup KA, Woo M, Hage A. Sleep disturbance symptoms in patients with heart failure. AACN Clinical Issues. 2003;14(4):477-487.</li> <li>Brostrom A, Stromberg A, Dalstrom U, Fridlund B. Sleep difficulties, daytime sleepiness, and health-related quality of life in patients with chronic heart failure. J Cardiovasc Nurs. 2004;19(4):234-242.</li> <li>Gheorghiade M, De LL, Fonarow GC, et al: Pathophysiologic targets in the early phase of acute heart failure syndromes. <em>Am J Cardiol </em>2005; 96:11G&ndash;17G</li> <li>Emerman CL: Treatment of the acute de- compensation of heart failure: Efficacy and pharmacoeconomics of early initiation of therapy in the emergency department. <em>Rev Cardiovasc Med </em>2003; 4(Suppl 7):S13&ndash;S20</li> <li>van den Berg-Emons, Hendrika JG, et al. &quot;Validity of ambulatory accelerometry to quantify physical activity in heart failure.&quot; <em>Scandinavian journal of rehabilitation medicine</em> 32.4 (2000): 187-192.</li> <li>Jehn, Melissa, et al. &quot;Accelerometer-based quantification of 6-minute walk test performance in patients with chronic heart failure: applicability in telemedicine.&quot; <em>Journal of cardiac failure</em> 15.4 (2009): 334-340.</li> <li>de Zambotti, Massimiliano, et al. &quot;Evaluation of a consumer fitness-tracking device to assess sleep in adults.&quot; <em>Chronobiology international</em> 32.7 (2015): 1024-1028.</li> </ul> <p>&nbsp;</p>

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