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Excision BioTherapeutics

Excision BioTherapeutics

One-time CRISPR cure for viral disease

Watertown, MA, US

Excision BioTherapeutics is a clinical-stage biotechnology company developing CRISPR-based gene-editing therapies to cure chronic viral infectious diseases by permanently eliminating viral DNA from infected cells.

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Problem Statement

Current treatments for chronic viral infectious diseases only manage symptoms and do not offer a cure, requiring lifelong therapy for patients.

Core Technology

CRISPR systems

Key Differentiators

Proprietary 'dual cut approach' to excise viral DNA from infected cells.

Clinical Focus

Infectious Disease; Virology

Company Info

Business Model
B2B
Total Funding
82,000,000
Website
www.excision.bio

Categories

Drug Discovery/Development

Disease Areas

Technologies

CRISPRGene EditingCRISPR-Cas9CRISPR-CasXNuclease

Clinical & IP

🔬

Clinical Validation

Phase 1/2 trial completed (5 patients); FDA Fast Track designation; met safety and biodistribution endpoints; HSV and HBV data presented at ASGCT 2025

MedStartr Index Score

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52

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Innovation

Clinical Benefit

Feasibility

Scalability

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