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Excision BioTherapeutics

Excision BioTherapeutics

One-time CRISPR cure for viral disease

Watertown, MA, US

Excision BioTherapeutics is a clinical-stage biotechnology company developing CRISPR-based gene-editing therapies to cure chronic viral infectious diseases by permanently eliminating viral DNA from infected cells.

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Problem Statement

Current treatments for chronic viral infectious diseases only manage symptoms and do not offer a cure, requiring lifelong therapy for patients.

Core Technology

CRISPR systems

Key Differentiators

Proprietary 'dual cut approach' to excise viral DNA from infected cells.

Clinical Focus

Infectious Disease; Virology

Company Info

Business Model
B2B
Total Funding
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Website
www.excision.bio

Categories

Drug Discovery/Development

Disease Areas

Technologies

CRISPR-Cas9CRISPR-CasXNucleaseGene Editing & CRISPR

Clinical & IP

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Clinical Validation

Phase 1/2 trial completed (5 patients); FDA Fast Track designation; met safety and biodistribution endpoints; HSV and HBV data presented at ASGCT 2025

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What do you think of Excision BioTherapeutics?

A HUGE part of what early stage companies, and even late stage ones, need and get on MedStartr is honest feedback from actual patients, clinicians, hospital leaders and industry insiders. It is very easy to get tunnel vision as a founder. Please tell the team that runs this company what you think.

Clinical Benefit Potential

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Feasibility

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Innovativeness

The distinguishing features, concept, or technology that differentiates the entry compared to others that already exist and are in widespread use.

Fundability

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Scalability

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Presentation Quality

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