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Oxford BioTherapeutics

Oxford BioTherapeutics

Precision cancer immunotherapy through target discovery

Oxford, CA, UK

Oxford BioTherapeutics (OBT) is a clinical-stage oncology company based in Oxford, UK, and San Jose, USA. It is dedicated to discovering and developing first-in-class antibody-based therapies for cancer, with a pipeline including immuno-oncology and antibody-drug conjugate therapies.

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How We Help

Problem Statement

Developing first-in-class antibody-based therapies to address unmet needs in cancer treatment.

Core Technology

Proprietary proteomic target discovery platform called OGAP®-Verify, based on one of the world's largest proprietary cancer membrane proteomic databases.

Key Differentiators

First-in-class antibody-based therapies for cancer; Proprietary proteomic target discovery platform (OGAP®-Verify)

Clinical Focus

Immuno-oncology; Antibody-drug conjugates

Company Info

Business Model
B2B
Total Funding
14,600,000
Website
www.oxfordbiotherapeutics.com/

Categories

Drug Discovery/Development

Disease Areas

Technologies

antibody-based therapiesimmuno-oncologyantibody-drug conjugatebispecificCAR-TADCC therapeuticsproteomicstarget discoveryOncologyAntibody TherapeuticsImmuno-oncologyTarget DiscoveryADCBispecific Antibodies

Clinical & IP

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Clinical Validation

Phase 1b active for OBT076 (CD205 ADC); FDA IND cleared; initial Phase 1 data: 7/18 patients clinical benefit, optimal dose 3.0 mg/kg, well tolerated; Phase 2a planned for NSCLC, ovarian, gastric cancers; Phase 1b with checkpoint inhibitor combinations shows near-complete responses.

MedStartr Index Score

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32

What do you think of Oxford BioTherapeutics?

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Innovation

Clinical Benefit

Feasibility

Scalability

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