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Pencil Biosciences

Pencil Biosciences

Safer gene editing, no breaks

Macclesfield, Cheshire, UK

Pencil Biosciences is a biotechnology company.

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How We Help

Problem Statement

To overcome the limitations of current gene-editing technologies, which often rely on creating DNA double-strand breaks or nicks to introduce new genetic material.

Core Technology

A fully synthetic, RNA-guided, non-CRISPR gene-editing system called ApGet, which is modular and smaller than Cas-based technologies.

Key Differentiators

Gene-editing platform introduces new genetic material without causing DNA double-strand breaks or nicks.; Non-CRISPR based system.; Significantly smaller than Cas-based technologies.; Modular and fully synthetic platform.; Highly efficient "knock-in" of donor DNA sequences.

Company Info

Business Model
Hybrid
Total Funding
10,400,000
Website
www.pencilbiosciences.com

Categories

Drug Discovery/Development

Disease Areas

Technologies

Gene EditingGenome ModulationRNA-guided SystemNon-CRISPRSynthetic Biology

Clinical & IP

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Clinical Validation

Platform-stage technology focused on oncology and genetic diseases. Founded 2018, raised £5.6M seed funding plus Innovate UK grant. Early-stage platform development; no clinical trials initiated yet.

MedStartr Index Score

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31

What do you think of Pencil Biosciences?

A HUGE part of what early stage companies, and even late stage ones, need and get on MedStartr is honest feedback from actual patients, clinicians, hospital leaders and industry insiders. It is very easy to get tunnel vision as a founder. Please tell the team that runs this company what you think.

Innovation

Clinical Benefit

Feasibility

Scalability

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