Pencil Biosciences

Safer gene editing, no breaks

Macclesfield, Cheshire, UK

Pencil Biosciences is a biotechnology company.

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Check out Pencil Biosciences on @MedStartr Today Pencil Biosciences is a biotechnology company. #RareDiseases #InfectiousDiseases #GeneticDisorders #CancerOncology #DrugDiscoveryDevelopment #MedMo #MedStartrVentures

https://www.medstartr.ai/s/y35WMg3R-Rk

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Problem Statement

To overcome the limitations of current gene-editing technologies, which often rely on creating DNA double-strand breaks or nicks to introduce new genetic material.

Core Technology

A fully synthetic, RNA-guided, non-CRISPR gene-editing system called ApGet, which is modular and smaller than Cas-based technologies.

Key Differentiators

Gene-editing platform introduces new genetic material without causing DNA double-strand breaks or nicks.; Non-CRISPR based system.; Significantly smaller than Cas-based technologies.; Modular and fully synthetic platform.; Highly efficient "knock-in" of donor DNA sequences.

Company Info

Business Model: Hybrid
Total Funding: Only accessible to MedStartr community members. Join now
Only accessible to MedStartr community members.
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Website: www.pencilbiosciences.com

Disease Areas

Rare Diseases Infectious Diseases Genetic Disorders Cancer & Oncology

Technologies

Genome ModulationRNA-guided SystemNon-CRISPRSynthetic BiologyGene Editing & CRISPR

Clinical & IP

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Clinical Validation

Platform-stage technology focused on oncology and genetic diseases. Founded 2018, raised £5.6M seed funding plus Innovate UK grant. Early-stage platform development; no clinical trials initiated yet.

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MedStartr Engagement Score

The MedStartr Index is a reflection of how the crowds that come to MedStartr everyday to find healthcare innovations reacted. Calculated by our AI agent Fyggy based on algorithms we have been building since 2012 and over 100 different factors, the math is proprietary and complex. Suffice to say, it has been found to be highly correlative with early stage company growth. What you see here is the public version. To learn more or to get deeper access to our predictive data on startup success for your fund or company, click here.

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A HUGE part of what early stage companies, and even late stage ones, need and get on MedStartr is honest feedback from actual patients, clinicians, hospital leaders and industry insiders. It is very easy to get tunnel vision as a founder. Please tell the team that runs this company what you think.

Clinical Benefit Potential

The potential for a project to have a large and significant impact on medical care, treatment, or prevention.

Feasibility

The likelihood that this will provide benefit for patients / care givers and that the founders can execute on their vision and plan.

Innovativeness

The distinguishing features, concept, or technology that differentiates the entry compared to others that already exist and are in widespread use.

Fundability

The reviewers' beliefs that the idea is fundable or can make it to sustainability without outside investment.

Scalability

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