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Twist Bioscience

The Amazon of DNA

South San Francisco, California, United States

Twist Bioscience is a public biotechnology company manufacturing synthetic DNA and DNA products using a proprietary semiconductor-based process. Their innovative method allows for faster and more affordable production of high-quality synthetic DNA, used in products like synthetic genes and antibody libraries for drug discovery.

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Problem Statement

Twist Bioscience addresses the limitations of traditional DNA synthesis regarding throughput, cost, and scalability, which previously hindered the industrialization and broader application of engineered biology. Their platform overcomes these challenges to make synthetic DNA production faster, more affordable, and at an industrial scale.

Core Technology

proprietary semiconductor-based synthetic DNA manufacturing process, writing DNA on a silicon chip

Key Differentiators

faster and more affordable manufacturing of high-quality synthetic DNA

Clinical Focus

Cancer Research (detection, diagnostics, MRD testing, liquid biopsy, tumor profiling, hereditary oncology), Infectious Diseases (detecting and surveilling novel viral pathogens, SARS-CoV-2, monkeypox, universal flu vaccines), Drug Discovery & Biologics (antibody discovery and optimization for autoimmune, metabolic, and neurological diseases), Rare Diseases (whole exome analysis and focused rare disease-related sequences).

Target Customers

A wide range of industries, including synthetic biology, biopharma (drug discovery, biologics), and NGS tools customers (for cancer research, infectious diseases, rare diseases).

Product Stage

Mature

Company Info

Business Model
Operates a digital-to-biological manufacturing model, providing synthetic DNA-based products and services. Business segments include Synthetic Biology, NGS Tools, and Biopharma Services. Aims to be a foundational B2B provider of synthetic DNA, often described as the 'Amazon of DNA.'
Founded
2011
Total Funding
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Website
www.twistbioscience.com/

Categories

Drug Discovery/Development

Disease Areas

Technologies

Synthetic DNANext-Generation Sequencing (NGS) PreparationAntibody LibrariesDNA SynthesisSynthetic BiologySilicon-Based TechnologyHigh-Throughput ProductionNext-Generation Sequencing Tools

Clinical & IP

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IP Protection

Strong patent portfolio.

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Innovativeness

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Fundability

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Scalability

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